Adil Khan 11 months ago
AdiKhanOfficial #FYP Ideas

Designing of ImmuneAid Blood Purifier Beetroot Syrup

In Pakistan, several critical platelet disorders are identified including thrombocytopenic purpura and dengue fever which is acquiring endemic situation causing considerable morbidity and mortality. Although the two conditions have different immunological pictures, but both share common pathology i.

Project Title

Designing of ImmuneAid Blood Purifier Beetroot Syrup

Project Area of Specialization

Biomedical Engineering

Project Summary

In Pakistan, several critical platelet disorders are identified including thrombocytopenic purpura and dengue fever which is acquiring endemic situation causing considerable morbidity and mortality. Although the two conditions have different immunological pictures, but both share common pathology i.e., significant drop in blood platelet counts lead to plasma leakage gives rise to shock and organ failure; life threatening haemorrhage can also occur.  Immunosuppressant like corticosteroids can be given but they are associated with sever side effects and in addition the immunity of the patient gets further compromised. The unavailability of effective therapeutic mediations for dengue and thrombocytopenic purpura results in searching of alternative therapies, i.e., herbal remedies. Beetroot (Beta vulgaris) has been used traditionally as healthy diet, it has been reported that beetroot can reduce systolic and diastolic blood pressure and other vascular parameters. Therefore, in the current project we are designing an Blood purifying Beetroot Syrup which can also enhance immunity of the individuals.  The rationale behind the project that in majority of the cases the pathological condition arises when the regulation of immune system get disturbed. So, the one of the objects of the study to improve the immune and blood parameters. To conduct project 40 healthy volunteers (consent taken) were selected and their complete blood count were analyzed and record the data, and then fresh beetroot extract are consuming till two months.  After the experimental period, their blood samples again collected to analyze complete blood count i.e.,  post beetroot consumption. In the second phase of the study, ImmuneAid Blood Purifier Beetroot Syrup will be prepared, and the quality of the ImmuneAid Blood Purifier Beetroot Syrup will be certified by Pakistan Council of Scientific and Industrial Research (PCSIR). The certified ImmuneAid Beetroot syrup will be given as adjunctive therapy in addition to conventional standard of care to patients of dengue and thrombocytopenic purpura (two other separate groups with consent). Hematologic parameters including platelet count will be recorded over a time of consumption.  After a month trial their blood profile including differential WBCs count, RBC count, platelets count, prothrombin time (PT), activated partial thromboplastin time (APTT), bleeding time (BT), and fibrinogen assay will be examined and analyzed on regular basis and their case history will also be maintained with timeline.

Project Objectives

  • To prepare the immune enhaning blood purifying natural syrup from Beetroot.
  • The Beetroot immune boosting syrup will improves blood profile of normal indvidulas
  • The ImmuneAid beetroot syrup will enhance the RBCs and pltelets in dangue and other paltet disorders.

Project Implementation Method

  • The selection of Healthy volunteer (with consent) and their complete blood profile analysis.
  • Consumption of beetroot extract and post consumption blood profile analysis.
  • Preparation of ImmuneAid blood purifier beetroot syrup (including Sheesham, Sandal, Neem, and Tulsi etc.)
  • Certification of the product by Pakistan Council of Scientific and Industrial Research (PCSIR).
  • The certified syrup will be given for consumption to patients of dengue feve and thrombocytopenic purpura (two other separate groups with consent).  
  • After a month trial their hematologic parameters will be analyzed including
  • differential WBCs count are performing using Leishman stain,
  • Total White blood cells, total red blood cells and platelet counts are recorded using neubauer chamber under light microscope.
  • Bleeding time will be recorded by Ivy’s method
  • prothrombin time (PT), activated partial thromboplastin time (APTT), bleeding time (BT), and fibrinogen assay will be performed using standard methods on regular basis
  • The patients' case history will also be maintained with time.

Benefits of the Project

Studnets vcan design and market the ImmuneAid blood purfier Beetroot syrup

The syrup can enhance or bost theimmunity in healthy as well as other hematological disorder especillay platelets disorder

the treatment of dengue fever and thrombocytopenic purpura can made possible naturally with less or no side effect of the mediaction. 

By enhancing immune responses, the syrup can also be helpful in treating pandemic ccondition like COVID 19. 

Technical Details of Final Deliverable

The final output of the project will be the Immune enhancing natural prodcut i.e., ImmuneAid blood purifier Beetroot syrup

The final Product prototype  after pasing through various developmental stages i.e., production, and validation) and after getting health certification and design validation,  approved by Pakistan Council of Scientific and Industrial Research (PCSIR) will be market or handover to pharmaceutical company. 

Final Deliverable of the Project

HW/SW integrated system

Core Industry

Medical

Other Industries

Food , Energy , Legal , Health

Core Technology

Others

Other Technologies

Sustainable Development Goals

Good Health and Well-Being for People, Industry, Innovation and Infrastructure

Required Resources

Item Name Type No. of Units Per Unit Cost (in Rs) Total (in Rs)
Compound Light Microscope Equipment16000060000
project publication charge Miscellaneous 11000010000
Total in (Rs) 70000
If you need this project, please contact me on contact@adikhanofficial.com
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