Adil Khan 9 months ago
AdiKhanOfficial #FYP Ideas

Development of Mechanoreceptors using Nanofibers for Artificial Skin

In recent years, the significance of nanofibers in designing ultra-sensitive sensors for human due to their good biocompatibility is being recognized globally. In this project, a novel approach will be introduced to design mechanoreceptors by fabricating biocompatible nanofibers from natural protein

Project Title

Development of Mechanoreceptors using Nanofibers for Artificial Skin

Project Area of Specialization

Wearables and Implantable

Project Summary

In recent years, the significance of nanofibers in designing ultra-sensitive sensors for human due to their good biocompatibility is being recognized globally. In this project, a novel approach will be introduced to design mechanoreceptors by fabricating biocompatible nanofibers from natural protein material Silk Cocoons to implant in artificial skin. Nanofibers would be generated using electrospinning technique and then in specific phase and dimension would be molded to develop artificial mechanoreceptor. Design of mechanoreceptors using nanofibers with bioinspired structural and functional features, which would enable such sensors to demonstrate perceptive characteristics alike to the human skin sensors. The designed sensor will be tested on artificial skin and an assessment of characteristics will be carried out. They would be able to detect the change in pressure with high sensitivity.

Project Objectives

The main objective of our project is the fabrication of bioinspired pressure sensor using biocompatible nanofibers developed from fibroin solution extracted from Bombyx mori silk cocoons.

Project Implementation Method

The complete project is divided into three main steps which are following:

  • Development of Biocompatible Nanofibers.
  • Integration of Nanofibers to develop artificial mechanoreceptors.
  • Implementation and testing on the artificial skin.

Benefits of the Project

Patients suffering from Diabetes Neuropathology, Merkel-Cell Carcinoma, Autism Spectrum Disorder, and Parkinson’s disease loss their tactile sensing. Also, the people who faced the acid attacks loss their skin and sensors for tactile sensation as well. Moreover, patients who wear prosthesis due to loss of their organs need to have tactile and pressure sensation as a normal human being. So, the developed artificial mechanoreceptor would be implanted in the prosthesis to restore the tactile and pressure sensation of the patient to carry out routine activities normally. Most importantly the designed artificial mechanoreceptor will be biocompatible, so it won’t cause any harmful effects. Also, this project would cause a wide-scale impact on wearable electronics as this could also be implanted in the robotic or e-skin.

Technical Details of Final Deliverable

The developed artificial mechanoreceptor would be designed to exhibit the following properties:

Physical Quantity

Value

Comments

Ultrahigh Sensitivity

?34.47kPa-1

For a wide range of pressure.

Pressure

<0.8Pa

Would detect ultralow pressure value.

Response Time

<30-50ms

Faster response time than the human fingertips.

Surface Area

N/A

Would be integrated over the large surface area.

Physical Quantity

Ultrahigh Sensitivity

Pressure

Response Time

Surface Area

Final Deliverable of the Project

Hardware System

Core Industry

Health

Other Industries

Core Technology

Wearables and Implantables

Other Technologies

Sustainable Development Goals

Good Health and Well-Being for People

Required Resources

Elapsed time in (days or weeks or month or quarter) since start of the project Milestone Deliverable
Month 1Collection and Study of LiteratureUnderstanding of what and how the work was done in that area and what novelty could be introduced.
Month 2Analysis of Proposed SchemeAnalysing and understanding the complete concepts involve in the project.
Month 3Fabrication of NanofibersEnlist the items and equipments required.
Month 4Fabrication of NanofibersAllocate resources for all the defined steps.
Month 5Fabrication of NanofibersOrder the items for import.
Month 6Implementation of Schemes\ModelDevelop Nanofibers.
Month 7Analysis & SimulationMold nanofibers to develop artificial mechanoreceptors.
Month 8Result FormulationTesting of the developed sensor on artificial skin.
Month 9Final Write-up and FYP Report SubmissionWriting complete details of the project to publish for the Research Paper.
If you need this project, please contact me on contact@adikhanofficial.com
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